Oral Chronotherapeutics: Future of Drug Delivery Systems
نویسندگان
چکیده
Chronotherapeutics refers to a treatment method in which in vivo drug availability is timed to match rhythms of disease in order to optimize therapeutic outcomes and minimize side effects. it is also known as pulsatile drug delivery system and it focuses on the release of a drug at particular time and at a particular site in order to maintain constant blood levels of a particular drug. They are future of drug delivery systems as these are self programmed oral drug delivery system designed to release a particular drug at a particular rate and at a particular time in order to maintain desired plasma levels by placing these systems in the oral cavity and increasing the patient compliance by avoiding repeated drug administration. The recent advances in oral pulsatile drug delivery technology are CODAS, ACCU-BREAK, SODAS, IPDAS, DMDS Technology.
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